Benzyl Bromide → (2-Benzylamino-5-propargyloxy-phenyl)-(4-isopropyl-phenyl)-methanone

HRID 285918Notes

Reaction equation

HRID 285918 reaction equation
[Br:23][CH2:24][c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1.[CH2:31]([N:32]([CH:33]([CH3:34])[CH3:35])[CH:36]([CH3:37])[CH3:38])[CH3:39].[NH2:1][c:2]1[c:3]([C:12](=[O:13])[c:14]2[cH:15][cH:16][c:17]([CH:20]([CH3:21])[CH3:22])[cH:18][cH:19]2)[cH:4][c:5]([O:8][CH2:9][C:10]#[CH:11])[cH:6][cH:7]1.[O:40]1[CH2:41][CH2:42][O:43][CH2:44][CH2:45]1>>[NH:1]([c:2]1[c:3]([C:12](=[O:13])[c:14]2[cH:15][cH:16][c:17]([CH:20]([CH3:21])[CH3:22])[cH:18][cH:19]2)[cH:4][c:5]([O:8][CH2:9][C:10]#[CH:11])[cH:6][cH:7]1)[CH2:24][c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1

Participants

5

Reactant 4

HCID 7498Benzyl BromideHCID 312751,4-DioxaneHCID 81531DiisopropylethylamineHCID 45139628(2-Amino-5-(prop-2-yn-1-yloxy)phenyl)(4-isopropylphenyl)methanone

Product 1

HCID 45140213(2-Benzylamino-5-propargyloxy-phenyl)-(4-isopropyl-phenyl)-methanone

Sources & evidence

ORD record
ord-5b81786c8ed9489e81531f966206d8cc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…