Methanol → 2-(4-{6-Amino-5-[1-(2,6-dichloro-3-fluoro-phenyl)ethoxy]-pyridin-3-yl}-pyrazol-1-yl)-propionic acid
Reaction equation
[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:38][OH:39].[CH3:3][O:4][C:5]([CH:6]([CH3:7])[n:8]1[n:9][cH:10][c:11](-[c:13]2[cH:14][n:15][c:16]([NH2:31])[c:17]([O:19][CH:20]([CH3:21])[c:22]3[c:23]([Cl:30])[c:24]([F:29])[cH:25][cH:26][c:27]3[Cl:28])[cH:18]2)[cH:12]1)=[O:32].[Li+:2].[OH-:1].[OH2:40]>>[O:4]=[C:5]([CH:6]([CH3:7])[n:8]1[n:9][cH:10][c:11](-[c:13]2[cH:14][n:15][c:16]([NH2:31])[c:17]([O:19][CH:20]([CH3:21])[c:22]3[c:23]([Cl:30])[c:24]([F:29])[cH:25][cH:26][c:27]3[Cl:28])[cH:18]2)[cH:12]1)[OH:32]Participants
7
Sources & evidence
- ORD record
- ord-51cc55d0fba549428ed9089bf5b20b3e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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