Dimethylformamide → tert-butyl N-(3-nitrobenzyl)-N-(trifluoroacetyl)glycinate

HRID 287224Notes

Reaction equation

HRID 287224 reaction equation
[Br:1][CH2:2][C:3](=[O:4])[O:5][C:6]([CH3:7])([CH3:8])[CH3:9].[C:27](=[O:28])([O-:29])[O-:30].[CH3:38][CH2:39][O:40][C:41]([CH3:42])=[O:43].[Cs+:31].[Cs+:32].[F:10][C:11]([C:12](=[O:13])[NH:14][CH2:15][c:16]1[cH:17][c:18]([N+:22](=[O:23])[O-:24])[cH:19][cH:20][cH:21]1)([F:25])[F:26].[O:33]=[CH:34][N:35]([CH3:36])[CH3:37]>>[CH2:2]([C:3](=[O:4])[O:5][C:6]([CH3:7])([CH3:8])[CH3:9])[N:14]([C:12]([C:11]([F:10])([F:25])[F:26])=[O:13])[CH2:15][c:16]1[cH:17][c:18]([N+:22](=[O:23])[O-:24])[cH:19][cH:20][cH:21]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 79177tert-Butyl bromoacetateHCID 104967Cesium cation2×HCID 57842617Acetamide, 2,2,2-trifluoro-N-[(3-nitrophenyl)methyl]-

Product 1

HCID 57842799tert-butyl N-(3-nitrobenzyl)-N-(trifluoroacetyl)glycinate

Sources & evidence

ORD record
ord-0d7a98b6f3124732a9ab1f6ce9938bff
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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