Chloride → 2-(4-Methoxyphenyl)-2-trifluoromethylpropionitrile

HRID 287257Notes

Reaction equation

HRID 287257 reaction equation
[CH2:24]([Cl:25])[Cl:26].[CH3:1][Si:2]([CH3:3])([CH3:4])[C:5]#[N:6].[Cl-:27].[Cl-:28].[Cl-:29].[Cl-:30].[Cl:7][C:8]([CH3:9])([C:10]([F:11])([F:12])[F:13])[c:14]1[cH:15][cH:16][c:17]([O:20][CH3:21])[cH:18][cH:19]1.[Na+:23].[OH-:22].[Ti+4:31]>>[C:5](#[N:6])[C:8]([CH3:9])([C:10]([F:11])([F:12])[F:13])[c:14]1[cH:15][cH:16][c:17]([O:20][CH3:21])[cH:18][cH:19]1

Participants

8

Reactant 7

HCID 312Chloride4×HCID 923Sodium ionHCID 961HydroxideHCID 6344DichloromethaneHCID 82115Trimethylsilyl cyanideHCID 114942Titanium cation (4+)HCID 138856001-Chloro-1-(4-methoxyphenyl)-1-trifluoromethylethane

Product 1

HCID 138856012-(4-Methoxyphenyl)-2-trifluoromethylpropionitrile

Sources & evidence

ORD record
ord-4900eb798ef54acb9184854511dfb37a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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