Chloride → 6-(5-Formyl-3-pyridin-2-yl-isoxazol-4-ylmethoxy)-nicotinonitrile

HRID 287260Notes

Reaction equation

HRID 287260 reaction equation
[C:37]([O:38][CH2:39][CH3:40])(=[O:41])[CH3:42].[CH2:49]([N+:50]([CH2:51][CH3:52])([CH2:53][CH3:54])[CH2:55][CH3:56])[c:57]1[cH:58][cH:59][cH:60][cH:61][cH:62]1.[CH3:43][C:44]([OH:45])([CH3:46])[CH3:47].[Cl-:48].[I+3:30]([O-:31])([O-:32])([O-:33])[O-:34].[Na+:35].[O:63]1[CH2:64][CH2:65][O:66][CH2:67][CH2:68]1.[OH2:36].[OH2:69].[Os:70](=[O:71])(=[O:72])(=[O:73])=[O:74].[n:1]1[c:2](-[c:7]2[n:8][o:9][c:10]([CH:22]=[CH:23][c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[c:11]2[CH2:12][O:13][c:14]2[n:15][cH:16][c:17]([C:18]#[N:19])[cH:20][cH:21]2)[cH:3][cH:4][cH:5][cH:6]1>>[n:1]1[c:2](-[c:7]2[n:8][o:9][c:10]([CH:22]=[O:31])[c:11]2[CH2:12][O:13][c:14]2[n:15][cH:16][c:17]([C:18]#[N:19])[cH:20][cH:21]2)[cH:3][cH:4][cH:5][cH:6]1

Participants

11

Reactant 10

HCID 312ChlorideHCID 923Sodium ionHCID 962Water2×HCID 6386tert-ButanolHCID 8857Ethyl AcetateHCID 17208BenzyltriethylammoniumHCID 30318Osmium TetroxideHCID 312751,4-DioxaneHCID 167232PeriodateHCID 667182066-[[5-(2-Phenylethenyl)-3-pyridin-2-yl-1,2-oxazol-4-yl]methoxy]pyridine-3-carbonitrile

Product 1

HCID 866462576-(5-Formyl-3-pyridin-2-yl-isoxazol-4-ylmethoxy)-nicotinonitrile

Sources & evidence

ORD record
ord-23b937951dad4e0389d399b8854b6ca8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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