Tetrahydrofuran → Tert-butyl 3-((2-chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methylene)azetidine-1-carboxylate
Reaction equation
[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH:25]([N-:26][CH:27]([CH3:28])[CH3:29])([CH3:30])[CH3:31].[Cl:1][c:2]1[n:3][c:4]([N:19]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)[c:5]2[c:6]([n:7]1)[cH:8][cH:9][c:10]([CH2:12][P:13](=[O:14])([O:15][CH3:16])[O:17][CH3:18])[n:11]2.[Li+:32].[O:33]=[C:34]1[CH2:35][N:36]([C:38](=[O:39])[O:40][C:41]([CH3:42])([CH3:43])[CH3:44])[CH2:37]1>>[Cl:1][c:2]1[n:3][c:4]([N:19]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)[c:5]2[c:6]([n:7]1)[cH:8][cH:9][c:10]([CH:12]=[C:34]1[CH2:35][N:36]([C:38](=[O:39])[O:40][C:41]([CH3:42])([CH3:43])[CH3:44])[CH2:37]1)[n:11]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-bea7894ecbbf46639bde559be7c631c2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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