Acetic Acid → Tert-butyl 4-cyclohexyl-4-hydroxypiperidine-1-carboxylate
Reaction equation
[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:27][C:28](=[O:29])[OH:30].[CH:6]1([Mg+:12])[CH2:7][CH2:8][CH2:9][CH2:10][CH2:11]1.[Cl-:5].[Cl:1][Ce:2]([Cl:3])[Cl:4].[O:13]=[C:14]1[CH2:15][CH2:16][N:17]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:18][CH2:19]1>>[CH:6]1([C:14]2([OH:13])[CH2:15][CH2:16][N:17]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:18][CH2:19]2)[CH2:7][CH2:8][CH2:9][CH2:10][CH2:11]1Participants
7
Sources & evidence
- ORD record
- ord-44f4d45ab04a4d0cbea5e1c928737c93
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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