Acetonitrile → Tert-butyl 4-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate

HRID 287976Notes

Reaction equation

HRID 287976 reaction equation
[Br:21][CH2:22][C:23](=[O:24])[O:25][CH3:26].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1.[CH3:14][CH2:15][N:16]([CH2:17][CH3:18])[CH2:19][CH3:20].[CH3:27][C:28]#[N:29]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([CH2:22][C:23](=[O:24])[O:25][CH3:26])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 6342AcetonitrileHCID 8471TriethylamineHCID 60984Methyl bromoacetateHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 46785870Tert-butyl 4-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-a2adc479d50e4c38aed80ba914c14dec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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