Tetrahydrofuran → 1-[4-[4-(4-Benzylmorpholin-2-yl)phenoxy]piperidin-1-yl]ethanone

HRID 288080Notes

Reaction equation

HRID 288080 reaction equation
[C:40]([CH3:41])(=[O:42])[N:43]1[CH2:44][CH2:45][CH:46]([OH:49])[CH2:47][CH2:48]1.[O:50]1[CH2:51][CH2:52][CH2:53][CH2:54]1.[OH:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[O:9][CH2:10][CH2:11][N:12]([CH2:14][c:15]3[cH:16][cH:17][cH:18][cH:19][cH:20]3)[CH2:13]2)[cH:6][cH:7]1.[c:21]1([P:22]([c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[cH:35][cH:36][cH:37][cH:38][cH:39]1>>[O:1]([c:2]1[cH:3][cH:4][c:5]([CH:8]2[O:9][CH2:10][CH2:11][N:12]([CH2:14][c:15]3[cH:16][cH:17][cH:18][cH:19][cH:20]3)[CH2:13]2)[cH:6][cH:7]1)[CH:46]1[CH2:45][CH2:44][N:43]([C:40]([CH3:41])=[O:42])[CH2:48][CH2:47]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 107492911-(4-Hydroxypiperidin-1-yl)ethan-1-oneHCID 669173494-(4-Benzyl-morpholin-2-yl)-phenol

Product 1

HCID 669173611-[4-[4-(4-Benzylmorpholin-2-yl)phenoxy]piperidin-1-yl]ethanone

Sources & evidence

ORD record
ord-1705e610e3ae4d5e8cd6588b85fd29fb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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