Triethylamine → 5,7-Dichloro-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one

HRID 288348Notes

Reaction equation

HRID 288348 reaction equation
[CH3:16][CH2:17][N:18]([CH2:19][CH3:20])[CH2:21][CH3:22].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:15]1)[C:7](=[O:14])[NH:8][CH2:9][C:10](=[O:13])[N:11]2[CH3:12].[P:23]([Cl:24])([Cl:25])([Cl:26])=[O:27]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:15]1)[C:7]([Cl:25])=[N:8][CH2:9][C:10](=[O:13])[N:11]2[CH3:12]

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 24813Phosphorus oxychlorideHCID 6142081H-1,4-Benzodiazepine-2,5-dione, 7-chloro-3,4-dihydro-1-methyl-

Product 1

HCID 123385855,7-Dichloro-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one

Sources & evidence

ORD record
ord-2d6e3f3b5206400cabfc126400dcc83a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…