Toluene → 4-(4-chloro-5-trifluoromethyl-pyrimidin-2-ylamino)-3-methoxy-N-(1-methyl-piperidin-4-yl)-benzamide
Reaction equation
[CH2:52]1[O:53][CH2:54][CH2:55][CH2:56]1.[CH3:45][c:46]1[cH:47][cH:48][cH:49][cH:50][cH:51]1.[CH:36]([N:37]([CH2:38][CH3:39])[CH:40]([CH3:41])[CH3:42])([CH3:43])[CH3:44].[Cl:1][c:2]1[n:3][c:4]([NH:12][c:13]2[c:14]([O:22][CH3:23])[cH:15][c:16]([C:17](=[O:18])[OH:19])[cH:20][cH:21]2)[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11].[NH2:28][CH:29]1[CH2:30][CH2:31][N:32]([CH3:35])[CH2:33][CH2:34]1.[S:24]([Cl:25])([Cl:26])=[O:27]>>[Cl:1][c:2]1[n:3][c:4]([NH:12][c:13]2[c:14]([O:22][CH3:23])[cH:15][c:16]([C:17](=[O:19])[NH:28][CH:29]3[CH2:30][CH2:31][N:32]([CH3:35])[CH2:33][CH2:34]3)[cH:20][cH:21]2)[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-8340097d8aac4ba0a236b65418769a40
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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