Hydrochloric Acid → Benzyl[4-(2-aminopyridin-4-yloxy)-2-fluorophenyl]carbamate

HRID 289038Notes

Reaction equation

HRID 289038 reaction equation
[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[O:9][C:10](=[O:11])[NH:12][c:13]1[c:14]([F:34])[cH:15][c:16]([O:17][c:18]2[cH:19][c:20]([NH:24][C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[n:21][cH:22][cH:23]2)[cH:32][cH:33]1.[CH3:35][CH2:36][O:37][C:38](=[O:39])[CH3:40].[ClH:1]>>[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[O:9][C:10](=[O:11])[NH:12][c:13]1[c:14]([F:34])[cH:15][c:16]([O:17][c:18]2[cH:19][c:20]([NH2:24])[n:21][cH:22][cH:23]2)[cH:32][cH:33]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 8857Ethyl AcetateHCID 57677355Tert-butyl [4-(4-benzyloxycarbonylamino-3-fluorophenoxy)pyridin-2-yl]carbamate

Product 1

HCID 57470855Benzyl[4-(2-aminopyridin-4-yloxy)-2-fluorophenyl]carbamate

Sources & evidence

ORD record
ord-1e637a1e5391414bab4b77e94a43a9aa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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