Ethylene Glycol → 4-(3-Bromo-imidazo[1,2-a]pyridin-6-ylamino)-cyclohexanol

HRID 289106Notes

Reaction equation

HRID 289106 reaction equation
[Br:1][c:2]1[cH:3][n:4][c:5]2[n:6]1[cH:7][c:8]([I:11])[cH:9][cH:10]2.[CH:24]([OH:25])([CH3:26])[CH3:27].[Cu:28][I:29].[NH2:16][CH:17]1[CH2:18][CH2:19][CH:20]([OH:23])[CH2:21][CH2:22]1.[OH:12][CH2:13][CH2:14][OH:15]>>[Br:1][c:2]1[cH:3][n:4][c:5]2[n:6]1[cH:7][c:8]([NH:16][CH:17]1[CH2:18][CH2:19][CH:20]([OH:23])[CH2:21][CH2:22]1)[cH:9][cH:10]2

Participants

6

Reactant 5

HCID 174Ethylene GlycolHCID 3776IsopropanolHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 812934-AminocyclohexanolHCID 684848303-Bromo-6-iodoimidazo[1,2-A]pyridine

Product 1

HCID 684826874-(3-Bromo-imidazo[1,2-a]pyridin-6-ylamino)-cyclohexanol

Sources & evidence

ORD record
ord-fe2c336a27b54571b5998b3b894d328b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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