Tetrahydrofuran → 2-((5-amino-3-bromo-7-iodo-5H-chromeno[2,3-b]pyridin-5-yl)methoxy)acetonitrile
Reaction equation
[Br:20][CH2:21][C:22]#[N:23].[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:24][C:25]([CH3:26])([O-:27])[CH3:28].[Li+:29].[NH2:1][C:2]1([CH2:18][OH:19])[c:3]2[cH:4][c:5]([I:17])[cH:6][cH:7][c:8]2[O:9][c:10]2[n:11][cH:12][c:13]([Br:16])[cH:14][c:15]21>>[NH2:1][C:2]1([CH2:18][O:19][CH2:21][C:22]#[N:23])[c:3]2[cH:4][c:5]([I:17])[cH:6][cH:7][c:8]2[O:9][c:10]2[n:11][cH:12][c:13]([Br:16])[cH:14][c:15]21Participants
6
Sources & evidence
- ORD record
- ord-036c9c07dbea4710b7a30c9ddefbcbdd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…