4-Bromophenol → Phenol, 4-(3-pyridinyl)-

HRID 289321Notes

Reaction equation

HRID 289321 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([OH:8])[cH:6][cH:7]1.[CH2:9]([Sn:10]([CH2:11][CH2:12][CH2:13][CH3:20])([c:14]1[cH:15][n:16][cH:17][cH:18][cH:19]1)[CH2:21][CH2:22][CH2:23][CH3:24])[CH2:25][CH2:26][CH3:27].[O:28]1[CH2:29][CH2:30][O:31][CH2:32][CH2:33]1.[Pd:34]([Cl:35])[Cl:36].[c:37]1([P:38]([c:39]2[cH:40][cH:41][cH:42][cH:43][cH:44]2)[c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)[cH:51][cH:52][cH:53][cH:54][cH:55]1.[c:56]1([P:57]([c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)[cH:70][cH:71][cH:72][cH:73][cH:74]1>>[c:2]1(-[c:14]2[cH:15][n:16][cH:17][cH:18][cH:19]2)[cH:3][cH:4][c:5]([OH:8])[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 78084-BromophenolHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 312751,4-DioxaneHCID 34838483-(Tributylstannyl)pyridine

Product 1

HCID 153040Phenol, 4-(3-pyridinyl)-

Sources & evidence

ORD record
ord-d7623c3b65824babb11d33d45107db8e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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