Tetrahydrofuran → 1-[1-(4-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl]-3-{3-[6-methoxy-7-(2-methoxyethoxy)quinazolin-4-ylthio]phenyl}urea
Reaction equation
[CH2:61]1[O:62][CH2:63][CH2:64][CH2:65]1.[CH3:27][O:28][c:29]1[cH:30][c:31]2[c:32]([S:44][c:45]3[cH:46][c:47]([NH2:48])[cH:49][cH:50][cH:51]3)[n:33][cH:34][n:35][c:36]2[cH:37][c:38]1[O:39][CH2:40][CH2:41][O:42][CH3:43].[CH3:52][N:53]([CH3:54])[c:55]1[cH:56][cH:57][n:58][cH:59][cH:60]1.[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][c:10]([C:23]([F:24])([F:25])[F:26])[cH:11][c:12]2[NH:13][C:14]([O:15][c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)=[O:22])[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][c:10]([C:23]([F:24])([F:25])[F:26])[cH:11][c:12]2[NH:13][C:14](=[O:22])[NH:48][c:47]2[cH:46][c:45]([S:44][c:32]3[c:31]4[cH:30][c:29]([O:28][CH3:27])[c:38]([O:39][CH2:40][CH2:41][O:42][CH3:43])[cH:37][c:36]4[n:35][cH:34][n:33]3)[cH:51][cH:50][cH:49]2)[cH:6][cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-55edb3ad62cb40bfa7f6c8b9faec1533
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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