Tetrahydrofuran → 1-tert-Butyloxycarbonyl-4-(3-aminopropyl)piperazine

HRID 291299Notes

Reaction equation

HRID 291299 reaction equation
[C:20]([CH3:21])([CH3:22])([CH3:23])[O:24][C:25](=[O:26])[N:27]1[CH2:28][CH2:29][N:30]([CH2:33][CH2:34][CH2:35][N:36]=[N+:37]=[N-:38])[CH2:31][CH2:32]1.[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[C:20]([CH3:21])([CH3:22])([CH3:23])[O:24][C:25](=[O:26])[N:27]1[CH2:28][CH2:29][N:30]([CH2:33][CH2:34][CH2:35][NH2:36])[CH2:31][CH2:32]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 86625340Tert-butyl 4-(3-azidopropyl)piperazine-1-carboxylate

Product 1

HCID 177509451-tert-Butyloxycarbonyl-4-(3-aminopropyl)piperazine

Sources & evidence

ORD record
ord-2c6dcc324a8447899aaa8174b1342ff2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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