Tetrahydrofuran → N-(3(2-((dimethylamino)methyl)-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-iodo-4-methylbenzamide
Reaction equation
[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH3:12][N:13]([CH3:14])[CH2:15][c:16]1[n:17](-[c:21]2[cH:22][c:23]([NH2:24])[cH:25][c:26]([C:28]([F:29])([F:30])[F:31])[cH:27]2)[cH:18][cH:19][n:20]1.[CH:32]([N:33]([CH2:34][CH3:35])[CH:36]([CH3:37])[CH3:38])([CH3:39])[CH3:40].[I:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[Cl:7])[cH:8][cH:9][c:10]1[CH3:11]>>[I:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:24][c:23]2[cH:22][c:21](-[n:17]3[c:16]([CH2:15][N:13]([CH3:12])[CH3:14])[n:20][cH:19][cH:18]3)[cH:27][c:26]([C:28]([F:29])([F:30])[F:31])[cH:25]2)[cH:8][cH:9][c:10]1[CH3:11]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-e44748efc4234937bbeb032b89b30ae5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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