Tetrahydrofuran → 1-(4-(2-Carbamoylpyridin-4-yloxy)-2,5-difluorophenyl)-3-(2-(4-fluorophenyl)acetyl)urea
Reaction equation
[CH2:80]1[O:81][CH2:82][CH2:83][CH2:84]1.[CH3:29][O:30][c:31]1[cH:32][cH:33][c:34]([CH2:35][NH:36][c:37]2[n:38][cH:39][n:40][c:41]([O:42][c:43]3[cH:44][cH:45][c:46]([NH:47][C:51](=[O:52])[NH:53][C:54]([CH2:55][c:56]4[cH:57][cH:58][c:59]([F:62])[cH:60][cH:61]4)=[O:63])[cH:48][c:49]3[F:50])[cH:64]2)[cH:65][cH:66]1.[CH:20]([N:21]([CH:22]([CH3:23])[CH3:24])[CH2:25][CH3:26])([CH3:27])[CH3:28].[F:67][c:68]1[cH:69][cH:70][c:71]([CH2:72][C:73]([N:74]=[C:75]=[O:76])=[O:77])[cH:78][cH:79]1.[NH2:1][c:2]1[cH:3][c:4]([F:19])[c:5]([O:6][c:7]2[cH:8][c:9]([C:13](=[O:14])[NH2:15])[n:10][cH:11][cH:12]2)[cH:16][c:17]1[F:18]>>[NH:1]([c:2]1[cH:3][c:4]([F:19])[c:5]([O:6][c:7]2[cH:8][c:9]([C:13](=[O:14])[NH2:15])[n:10][cH:11][cH:12]2)[cH:16][c:17]1[F:18])[C:51](=[O:52])[NH:53][C:54]([CH2:55][c:56]1[cH:57][cH:58][c:59]([F:62])[cH:60][cH:61]1)=[O:63]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-5d43e3328b49477d856443f4baf6ceef
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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