Hydrochloric Acid → N-((1RS,2SR)-2-hydroxy-2-(4-phenoxyphenyl)-1-((4-(trifluoromethyl)phenyl)methyl)ethyl)-4-fluoro-1-naphthalenecarboxamide
Reaction equation
[CH2:44]([N:45]=[C:46]=[N:47][CH2:48][CH2:49][CH2:50][N:51]([CH3:52])[CH3:53])[CH3:54].[CH3:65][C:66]#[N:67].[ClH:43].[F:29][c:30]1[cH:31][cH:32][c:33]([C:40](=[O:41])[OH:42])[c:34]2[cH:35][cH:36][cH:37][cH:38][c:39]12.[NH2:1][CH:2]([CH:3]([OH:4])[c:5]1[cH:6][cH:7][c:8]([O:11][c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[cH:9][cH:10]1)[CH2:18][c:19]1[cH:20][cH:21][c:22]([C:25]([F:26])([F:27])[F:28])[cH:23][cH:24]1.[OH2:68].[OH:55][n:56]1[c:57]2[cH:58][cH:59][cH:60][cH:61][c:62]2[n:63][n:64]1>>[NH:1]([CH:2]([CH:3]([OH:4])[c:5]1[cH:6][cH:7][c:8]([O:11][c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[cH:9][cH:10]1)[CH2:18][c:19]1[cH:20][cH:21][c:22]([C:25]([F:26])([F:27])[F:28])[cH:23][cH:24]1)[C:40]([c:33]1[cH:32][cH:31][c:30]([F:29])[c:39]2[c:34]1[cH:35][cH:36][cH:37][cH:38]2)=[O:41]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-0d8c9a47ec8148e795684456ca469068
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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