Acetic Acid → 2-[(1-{[1-(4-Chlorophenyl)cyclopropyl]carbonyl}-3-hydroxypyrrolidin-3-yl)methyl]nicotinic acid
Reaction equation
[CH2:11]([Li:12])[CH2:13][CH2:14][CH3:15].[CH2:59]1[O:60][CH2:61][CH2:62][CH2:63]1.[CH3:16][c:17]1[c:18]([C:19](=[O:20])[OH:21])[cH:22][cH:23][cH:24][n:25]1.[CH3:1][C:2]1([CH3:3])[CH2:4][CH2:5][CH2:6][C:7]([CH3:8])([CH3:9])[NH:10]1.[CH3:44][C:45](=[O:46])[OH:47].[CH3:53][CH2:54][CH2:55][CH2:56][CH2:57][CH3:58].[Cl:26][c:27]1[cH:28][cH:29][c:30]([C:33]2([C:36](=[O:37])[N:38]3[CH2:39][C:40](=[O:43])[CH2:41][CH2:42]3)[CH2:34][CH2:35]2)[cH:31][cH:32]1.[Na+:52].[O-:48][C:49]([OH:50])=[O:51]>>[CH2:16]([c:17]1[c:18]([C:19](=[O:20])[OH:21])[cH:22][cH:23][cH:24][n:25]1)[C:40]1([OH:43])[CH2:39][N:38]([C:36]([C:33]2([c:30]3[cH:29][cH:28][c:27]([Cl:26])[cH:32][cH:31]3)[CH2:34][CH2:35]2)=[O:37])[CH2:42][CH2:41]1Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-e675624718914e44a6ff9f99f511f1f7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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