Tetrahydrofuran → 4-[4-(5-Cyclohexylcarbamoyl-3-methylpyrazol-1-yl)phenoxy]piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:42]([CH3:43])([CH3:44])([CH3:45])[O:46][C:47](=[O:48])[N:49]1[CH2:50][CH2:51][CH:52]([OH:55])[CH2:53][CH2:54]1.[CH:1]1([NH:7][C:8](=[O:9])[c:10]2[n:11](-[c:16]3[cH:17][cH:18][c:19]([OH:22])[cH:20][cH:21]3)[n:12][c:13]([CH3:15])[cH:14]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[O:56]1[CH2:57][CH2:58][CH2:59][CH2:60]1.[c:23]1([P:24]([c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[cH:37][cH:38][cH:39][cH:40][cH:41]1>>[CH:1]1([NH:7][C:8](=[O:9])[c:10]2[n:11](-[c:16]3[cH:17][cH:18][c:19]([O:22][CH:52]4[CH2:51][CH2:50][N:49]([C:47]([O:46][C:42]([CH3:43])([CH3:44])[CH3:45])=[O:48])[CH2:54][CH2:53]4)[cH:20][cH:21]3)[n:12][c:13]([CH3:15])[cH:14]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-bbbe252b3c59410bbbdd8b9a7b660561
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…