Hydroxide → 4-((3-Fluoro-4-(5-(1-phenylcyclopropyl)[1,3]thiazolo[5,4-b]pyridin-2-yl)phenyl)amino)-4-oxobutanoic acid
Reaction equation
[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[F:1][c:2]1[cH:3][c:4]([NH:26][C:27]([CH2:28][CH2:29][C:30](=[O:31])[O:32][CH3:33])=[O:34])[cH:5][cH:6][c:7]1-[c:8]1[s:9][c:10]2[n:11][c:12]([C:17]3([c:20]4[cH:21][cH:22][cH:23][cH:24][cH:25]4)[CH2:18][CH2:19]3)[cH:13][cH:14][c:15]2[n:16]1.[Li+:43].[OH-:42].[OH2:40].[OH2:41]>>[F:1][c:2]1[cH:3][c:4]([NH:26][C:27]([CH2:28][CH2:29][C:30](=[O:31])[OH:32])=[O:34])[cH:5][cH:6][c:7]1-[c:8]1[s:9][c:10]2[n:11][c:12]([C:17]3([c:20]4[cH:21][cH:22][cH:23][cH:24][cH:25]4)[CH2:18][CH2:19]3)[cH:13][cH:14][c:15]2[n:16]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-600f885837e048b9b2eda6f664c49176
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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