Dichloromethane → N-[4-(1-ethyl-4-{2-[4-(4-morpholinylmethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}-1H-pyrazol-3-yl)phenyl]-2,2-dimethylpropanamide
Reaction equation
[C:44]([C:45]([CH3:46])([CH3:47])[CH3:48])(=[O:49])[Cl:50].[CH2:1]([CH3:2])[n:3]1[n:4][c:5](-[c:30]2[cH:31][cH:32][c:33]([NH2:36])[cH:34][cH:35]2)[c:6](-[c:8]2[c:9]3[c:10]([n:11][cH:12][cH:13]2)[nH:14][c:15](-[c:17]2[cH:18][cH:19][c:20]([CH2:23][N:24]4[CH2:25][CH2:26][O:27][CH2:28][CH2:29]4)[cH:21][cH:22]2)[cH:16]3)[cH:7]1.[CH2:51]([Cl:52])[Cl:53].[CH3:37][CH2:38][N:39]([CH2:40][CH3:41])[CH2:42][CH3:43].[CH3:54][N:55]([c:56]1[cH:57][cH:58][n:59][cH:60][cH:61]1)[CH3:62]>>[CH2:1]([CH3:2])[n:3]1[n:4][c:5](-[c:30]2[cH:31][cH:32][c:33]([NH:36][C:44]([C:45]([CH3:46])([CH3:47])[CH3:48])=[O:49])[cH:34][cH:35]2)[c:6](-[c:8]2[c:9]3[c:10]([n:11][cH:12][cH:13]2)[nH:14][c:15](-[c:17]2[cH:18][cH:19][c:20]([CH2:23][N:24]4[CH2:25][CH2:26][O:27][CH2:28][CH2:29]4)[cH:21][cH:22]2)[cH:16]3)[cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-a882281399e64c5cbdfc4226ebb5d564
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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