Methanol → 8-Chloro-3-(difluoromethoxy)-1,5-naphthyridine
Reaction equation
[C:21](=[O:22])([O-:23])[O-:24].[CH3:35][OH:36].[Cl:1][C:2]([C:3]([O-:4])=[O:5])([F:6])[F:7].[Cl:32][CH2:33][Cl:34].[Cl:9][c:10]1[cH:11][cH:12][n:13][c:14]2[cH:15][c:16]([OH:20])[cH:17][n:18][c:19]12.[Cs+:25].[Cs+:26].[Na+:8].[O:27]=[CH:28][N:29]([CH3:30])[CH3:31]>>[CH:2]([F:6])([F:7])[O:20][c:16]1[cH:15][c:14]2[n:13][cH:12][cH:11][c:10]([Cl:9])[c:19]2[n:18][cH:17]1Participants
9
Sources & evidence
- ORD record
- ord-6644e33555f940df924ff33b6f6124f4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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