Tetrahydrofuran → 4-(2-fluoro-4-(methylthio)phenylamino)-1-methyl-6-oxo-N-(2-(vinyloxy)ethoxy)-1,6-dihydropyridazine-3-carboxamide
Reaction equation
[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:31][Si:32]([N-:33][Si:34]([CH3:35])([CH3:36])[CH3:37])([CH3:38])[CH3:39].[CH:23](=[CH2:24])[O:25][CH2:26][CH2:27][O:28][NH2:29].[F:1][c:2]1[c:3]([NH:10][c:11]2[c:12]([C:19]([O:21][CH3:20])=[O:22])[n:13][n:14]([CH3:18])[c:15](=[O:17])[cH:16]2)[cH:4][cH:5][c:6]([S:8][CH3:9])[cH:7]1.[Li+:30]>>[F:1][c:2]1[c:3]([NH:10][c:11]2[c:12]([C:19](=[O:21])[NH:29][O:28][CH2:27][CH2:26][O:25][CH:23]=[CH2:24])[n:13][n:14]([CH3:18])[c:15](=[O:17])[cH:16]2)[cH:4][cH:5][c:6]([S:8][CH3:9])[cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-49a327f828e64990b167f76fd9c4ec0b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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