Hydrochloric Acid → 4-benzyl-3-[2-(3,4-dihydro-1H-[1]benzothiolo[2,3-c]pyridin-2-ylsulfonylmethyl)-3-methylbutanoyl]-1,3-oxazolidin-2-one

HRID 295190Notes

Reaction equation

HRID 295190 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[CH:8]1[N:9]([C:14]([CH:15]([CH:16]([CH3:17])[CH3:18])[CH2:19][S:20](=[O:21])(=[O:22])[Cl:23])=[O:24])[C:10](=[O:13])[O:11][CH2:12]1.[CH2:26]1[NH:27][CH2:28][CH2:29][c:30]2[c:31]1[s:32][c:33]1[c:34]2[cH:35][cH:36][cH:37][cH:38]1.[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[Cl:46][CH2:47][Cl:48].[ClH:25]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[CH:8]1[N:9]([C:14]([CH:15]([CH:16]([CH3:17])[CH3:18])[CH2:19][S:20](=[O:21])(=[O:22])[N:27]2[CH2:26][c:31]3[c:30]([c:34]4[c:33]([s:32]3)[cH:38][cH:37][cH:36][cH:35]4)[CH2:29][CH2:28]2)=[O:24])[C:10](=[O:13])[O:11][CH2:12]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 8471TriethylamineHCID 4132821,2,3,4-Tetrahydro[1]benzothieno[2,3-c]pyridineHCID 226466772-(4-Benzyl-2-oxo-1,3-oxazolidine-3-carbonyl)-3-methylbutane-1-sulfonyl chloride

Product 1

HCID 227197804-benzyl-3-[2-(3,4-dihydro-1H-[1]benzothiolo[2,3-c]pyridin-2-ylsulfonylmethyl)-3-methylbutanoyl]-1,3-oxazolidin-2-one

Sources & evidence

ORD record
ord-de85ba44c7aa47128eb0eb6513c92412
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…