Dichloromethane → 1-Boc-2-Formylpyrrolidine

HRID 295714Notes

Reaction equation

HRID 295714 reaction equation
[C:30](=[O:31])([O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[N:37]1[CH:38]([CH2:39][OH:40])[CH2:41][CH2:42][CH2:43]1.[CH2:23]([N:24]([CH2:25][CH3:26])[CH2:27][CH3:28])[CH3:29].[CH3:1][C:2]([O:3][C:4]([O:5][C:6]([O:7][C:8]([CH3:9])([CH3:10])[CH3:11])=[O:12])=[O:13])([CH3:14])[CH3:15].[Cl:44][CH2:45][Cl:46].[NH:16]1[CH2:17][CH2:18][CH2:19][CH:20]1[CH2:21][OH:22]>>[C:30](=[O:31])([O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[N:37]1[CH:38]([CH:39]=[O:40])[CH2:41][CH2:42][CH2:43]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 90495Di-tert-butyl dicarbonateHCID 90908ProlinolHCID 550865tert-Butyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate

Product 1

HCID 42278151-Boc-2-Formylpyrrolidine

Sources & evidence

ORD record
ord-4e13a8f9d20b40c2a758538813d60521
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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