4-Bromoanisole → 1-Benzyl-4-(4-methoxyphenyl)piperidin-4-ol
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1.[CH2:11]([c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)[N:18]1[CH2:19][CH2:20][C:21](=[O:24])[CH2:22][CH2:23]1.[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[Mg:10]>>[c:2]1([C:21]2([OH:24])[CH2:20][CH2:19][N:18]([CH2:11][c:12]3[cH:13][cH:14][cH:15][cH:16][cH:17]3)[CH2:23][CH2:22]2)[cH:3][cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-a12cd7c903d9420aa4d8a71706954c2b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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