2,5-Dichlorobenzoic acid → 2,5-dichloro-N-[3-(2-methoxyethyl)-5-methyl-1,3-thiazol-2-ylidene]benzamide

HRID 295855Notes

Reaction equation

HRID 295855 reaction equation
[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH3:27][O:28][CH2:29][CH2:30][n:31]1[c:32](=[NH:37])[s:33][c:34]([CH3:36])[cH:35]1.[CH3:38][CH2:39][N:40]([CH2:41][CH3:42])[CH2:43][CH3:44].[Cl:12][c:13]1[cH:14][cH:15][c:16]([Cl:17])[cH:18][c:19]1[C:20]([Cl:21])=[O:22].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][c:8]([Cl:11])[cH:9][cH:10]1.[S:23]([Cl:24])([Cl:25])=[O:26]>>[Cl:1][c:2]1[c:3]([C:4](=[O:6])[N:37]=[c:32]2[n:31]([CH2:30][CH2:29][O:28][CH3:27])[cH:35][c:34]([CH3:36])[s:33]2)[cH:7][c:8]([Cl:11])[cH:9][cH:10]1

Participants

7

Reactant 6

HCID 57842,5-Dichlorobenzoic acidHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 179452,5-Dichlorobenzoyl chlorideHCID 24386Thionyl ChlorideHCID 668599523-(2-methoxyethyl)-5-methylthiazol-2(3H)-imine

Product 1

HCID 686231202,5-dichloro-N-[3-(2-methoxyethyl)-5-methyl-1,3-thiazol-2-ylidene]benzamide

Sources & evidence

ORD record
ord-ff5ba5a19ef043eea8e3d53a69105fcc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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