Triethylamine → 2-Chloro-4-(3-dimethylaminopropyn-1-yl)-benzoic acid methyl ester

HRID 296001Notes

Reaction equation

HRID 296001 reaction equation
[CH3:13][N:14]([CH2:15][C:16]#[CH:17])[CH3:18].[CH3:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25].[CH3:1][O:2][C:3]([c:4]1[c:5]([Cl:11])[cH:6][c:7]([Br:10])[cH:8][cH:9]1)=[O:12].[Cu:26][I:27]>>[CH3:1][O:2][C:3]([c:4]1[c:5]([Cl:11])[cH:6][c:7]([C:17]#[C:16][CH2:15][N:14]([CH3:13])[CH3:18])[cH:8][cH:9]1)=[O:12]

Participants

5

Reactant 4

HCID 8471TriethylamineHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 81643N,N-DimethylpropargylamineHCID 22058730Methyl 4-Bromo-2-chlorobenzoate

Product 1

HCID 539792842-Chloro-4-(3-dimethylaminopropyn-1-yl)-benzoic acid methyl ester

Sources & evidence

ORD record
ord-cee5f24e5bf54d71b7fb970889ae47b9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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