Acetonitrile → 4-Amino-6-(4-chlorophenyl)-5-fluoro-3-vinylpyridine-2-carboxylic acid methyl ester
Reaction equation
[CH2:21]([CH2:22][CH2:34][CH3:35])[Sn:23]([CH2:24][CH2:25][CH2:26][CH3:27])([CH2:28][CH2:29][CH2:30][CH3:31])[CH:32]=[CH2:33].[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7](-[c:14]2[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[c:8]([F:13])[c:9]([NH2:12])[c:10]1[Cl:11].[CH3:36][C:37]#[N:38].[Pd:39]([Cl:40])[Cl:41].[c:42]1([P:43]([c:44]2[cH:45][cH:46][cH:47][cH:48][cH:49]2)[c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[cH:56][cH:57][cH:58][cH:59][cH:60]1.[c:61]1([P:62]([c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)[c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)[cH:75][cH:76][cH:77][cH:78][cH:79]1>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7](-[c:14]2[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[c:8]([F:13])[c:9]([NH2:12])[c:10]1[CH:21]=[CH2:22]Participants
6
Sources & evidence
- ORD record
- ord-e181ec3c163e4375a3bbff83c153c204
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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