Diisopropylamine → 3-Cyano-6,7-dimethoxy-4-[6chloro-4-(3-methoxyprop-1-ynyl)-2,3-methylene dioxyanilino]quinoline
Reaction equation
[CH2:29]([C:30]#[CH:31])[O:32][CH3:33].[CH3:83][CH2:84][O:85][C:86](=[O:87])[CH3:88].[CH:34]([NH:35][CH:36]([CH3:37])[CH3:38])([CH3:39])[CH3:40].[Cl:1][c:2]1[cH:3][c:4]([I:28])[c:5]2[c:6]([c:7]1[NH:8][c:9]1[c:10]([C:23]#[N:24])[cH:11][n:12][c:13]3[cH:14][c:15]([O:21][CH3:22])[c:16]([O:19][CH3:20])[cH:17][c:18]13)[O:25][CH2:26][O:27]2.[I-:41].[Pd:42]([Cl:43])[Cl:44].[c:45]1([P:46]([c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[cH:59][cH:60][cH:61][cH:62][cH:63]1.[c:64]1([P:65]([c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)[c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)[cH:78][cH:79][cH:80][cH:81][cH:82]1>>[Cl:1][c:2]1[cH:3][c:4]([C:31]#[C:30][CH2:29][O:32][CH3:33])[c:5]2[c:6]([c:7]1[NH:8][c:9]1[c:10]([C:23]#[N:24])[cH:11][n:12][c:13]3[cH:14][c:15]([O:21][CH3:22])[c:16]([O:19][CH3:20])[cH:17][c:18]13)[O:25][CH2:26][O:27]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-a7dec7c7cff6410399fde8905d1799b1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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