Tetrahydrofuran → 7-Nitroisochroman

HRID 296919Notes

Reaction equation

HRID 296919 reaction equation
[CH2:53]1[O:54][CH2:55][CH2:56][CH2:57]1.[O:15]=[C:16]1[NH:17][C:18](=[O:19])[CH2:20][CH2:21]1.[O:41]=[C:42]([O:43][CH2:44][CH3:45])[N:46]=[N:47][C:48]([O:49][CH2:50][CH3:51])=[O:52].[OH:1][CH2:2][c:3]1[c:4]([CH2:12][CH2:13][OH:14])[cH:5][cH:6][c:7]([N+:9](=[O:10])[O-:11])[cH:8]1.[c:22]1([P:23]([c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[cH:36][cH:37][cH:38][cH:39][cH:40]1>>[CH2:2]1[c:3]2[c:4]([cH:5][cH:6][c:7]([N+:9](=[O:10])[O-:11])[cH:8]2)[CH2:12][CH2:13][O:14]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 11439SuccinimideHCID 11776TriphenylphosphineHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 222696612-(2-(Hydroxymethyl)-4-nitrophenyl)ethanol

Product 1

HCID 9017397-Nitroisochroman

Sources & evidence

ORD record
ord-8290ecfbe1164e79b4c214dfa906e094
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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