Toluene → 4-Chloro-2-(2-methoxy-phenyl)-7-methyl-quinazoline

HRID 298158Notes

Reaction equation

HRID 298158 reaction equation
[CH3:1][O:2][c:3]1[c:4](-[c:9]2[n:10][c:11]3[cH:12][c:13]([CH3:20])[cH:14][cH:15][c:16]3[c:17](=[O:19])[nH:18]2)[cH:5][cH:6][cH:7][cH:8]1.[CH3:35][c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1.[CH:21]([N:22]([CH:23]([CH3:24])[CH3:25])[CH2:26][CH3:27])([CH3:28])[CH3:29].[P:30]([Cl:31])([Cl:32])([Cl:33])=[O:34]>>[CH3:1][O:2][c:3]1[c:4](-[c:9]2[n:10][c:11]3[cH:12][c:13]([CH3:20])[cH:14][cH:15][c:16]3[c:17]([Cl:32])[n:18]2)[cH:5][cH:6][cH:7][cH:8]1

Participants

5

Reactant 4

HCID 1140TolueneHCID 24813Phosphorus oxychlorideHCID 81531DiisopropylethylamineHCID 136105219HCID 136105219, compound

Product 1

HCID 592128574-Chloro-2-(2-methoxy-phenyl)-7-methyl-quinazoline

Sources & evidence

ORD record
ord-c975093ba2144e3a9ad61840c0671b3a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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