Tetrahydrofuran → 1-(3-(2-cyanopropan-2-yl)-1-phenyl-1H-pyrazol-5-yl)-3-(3-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)urea
Reaction equation
[C:23](#[N:24])[C:25]([CH3:26])([CH3:27])[c:28]1[n:29][n:30](-[c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[c:31]([NH:33][C:34]([O:35][c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)=[O:36])[cH:32]1.[CH2:49]1[O:50][CH2:51][CH2:52][CH2:53]1.[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[cH:17][c:18]([NH2:19])[cH:20][cH:21][cH:22]3)[n:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14].[CH3:54][N:55]([c:56]1[cH:57][cH:58][n:59][cH:60][cH:61]1)[CH3:62]>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[cH:17][c:18]([NH:19][C:34]([NH:33][c:31]4[n:30](-[c:43]5[cH:44][cH:45][cH:46][cH:47][cH:48]5)[n:29][c:28]([C:25]([C:23]#[N:24])([CH3:26])[CH3:27])[cH:32]4)=[O:35])[cH:20][cH:21][cH:22]3)[n:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-c8e61f90470c4567a8c99105b12ba4c3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…