Chloride → 4'-[3-(3-Hydroxy-3-isopropyl-1-pyrrolidinyl)propoxy][1,1'-biphenyl]-4-carbonitrile

HRID 298296Notes

Reaction equation

HRID 298296 reaction equation
[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH:26]([CH3:27])([CH3:28])[Mg+:29].[Cl-:25].[O:1]=[C:2]1[CH2:3][N:4]([CH2:7][CH2:8][CH2:9][O:10][c:11]2[cH:12][cH:13][c:14](-[c:17]3[cH:18][cH:19][c:20]([C:23]#[N:24])[cH:21][cH:22]3)[cH:15][cH:16]2)[CH2:5][CH2:6]1>>[OH:1][C:2]1([CH:26]([CH3:27])[CH3:28])[CH2:3][N:4]([CH2:7][CH2:8][CH2:9][O:10][c:11]2[cH:12][cH:13][c:14](-[c:17]3[cH:18][cH:19][c:20]([C:23]#[N:24])[cH:21][cH:22]3)[cH:15][cH:16]2)[CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 99230964'-[3-(3-Oxo-1-pyrrolidinyl)propoxy][1,1'-biphenyl]-4-carbonitrileHCID 178461726HCID 178461726, compound

Product 1

HCID 102922444'-[3-(3-Hydroxy-3-isopropyl-1-pyrrolidinyl)propoxy][1,1'-biphenyl]-4-carbonitrile

Sources & evidence

ORD record
ord-92938516d263462e84a42254d92a3d48
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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