Dimethylformamide → N-(4-Fluorophenyl)-N'-[4-({2-[(pyrrolidin-1-ylcarbonyl)amino]pyridin-4-yl}oxy)phenyl]cyclopropane-1,1-dicarboxamide
Reaction equation
[CH3:72][N:73]([CH3:74])[CH:75]=[O:76].[CH:39]([N:40]([CH:41]([CH3:42])[CH3:43])[CH2:44][CH3:45])([CH3:46])[CH3:47].[F:23][c:24]1[cH:25][cH:26][c:27]([NH:30][C:31](=[O:32])[C:33]2([C:36](=[O:37])[OH:38])[CH2:34][CH2:35]2)[cH:28][cH:29]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([O:6][c:7]2[cH:8][c:9]([NH:13][C:14](=[O:15])[N:16]3[CH2:17][CH2:18][CH2:19][CH2:20]3)[n:10][cH:11][cH:12]2)[cH:21][cH:22]1.[P-:48]([F:49])([F:50])([F:51])([F:52])([F:53])[F:54].[n:55]1([O:56][C:57]([N:58]([CH3:59])[CH3:60])=[N+:61]([CH3:62])[CH3:63])[c:64]2[cH:65][cH:66][cH:67][cH:68][c:69]2[n:70][n:71]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([O:6][c:7]2[cH:8][c:9]([NH:13][C:14](=[O:15])[N:16]3[CH2:17][CH2:18][CH2:19][CH2:20]3)[n:10][cH:11][cH:12]2)[cH:21][cH:22]1)[C:36]([C:33]1([C:31]([NH:30][c:27]2[cH:26][cH:25][c:24]([F:23])[cH:29][cH:28]2)=[O:32])[CH2:34][CH2:35]1)=[O:37]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-514eae2ca5ea42f99fb12c7f5475ac12
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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