Citric Acid → methyl 4-[(2-phenyl-1H-indol-1-yl)methyl]benzoate

HRID 299084Notes

Reaction equation

HRID 299084 reaction equation
[Br:18][CH2:19][c:20]1[cH:21][cH:22][c:23]([C:24](=[O:25])[O:26][CH3:27])[cH:28][cH:29]1.[CH3:43][N:44]([CH3:45])[CH:46]=[O:47].[H-:16].[Na+:17].[O:48]1[CH2:49][CH2:50][CH2:51][CH2:52]1.[OH:30][C:31]([CH2:32][C:33]([C:34](=[O:35])[OH:36])([CH2:37][C:38](=[O:39])[OH:40])[OH:41])=[O:42].[c:1]1(-[c:7]2[nH:8][c:9]3[cH:10][cH:11][cH:12][cH:13][c:14]3[cH:15]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[n:8]([CH2:19][c:20]3[cH:21][cH:22][c:23]([C:24](=[O:25])[O:26][CH3:27])[cH:28][cH:29]3)[c:9]3[cH:10][cH:11][cH:12][cH:13][c:14]3[cH:15]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

8

Reactant 7

HCID 311Citric AcidHCID 923Sodium ionHCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 136982-PhenylindoleHCID 166653HydrideHCID 256687Methyl 4-(bromomethyl)benzoate

Product 1

HCID 23111749methyl 4-[(2-phenyl-1H-indol-1-yl)methyl]benzoate

Sources & evidence

ORD record
ord-4fb087fe3fbf4768b448e7ca4940c285
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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