Hydrochloric Acid → 1,1,1,3,3,3-Hexafluoro-2-[2-(2-methyl-4-thiophen-2-ylsulfonylpiperazin-1-yl)pyrimidin-5-yl]propan-2-ol
Reaction equation
[CH3:2][CH:3]1[NH:4][CH2:5][CH2:6][N:7]([S:9](=[O:10])(=[O:11])[c:12]2[s:13][cH:14][cH:15][cH:16]2)[CH2:8]1.[CH:34]([N:35]([CH2:36][CH3:37])[CH:38]([CH3:39])[CH3:40])([CH3:41])[CH3:42].[Cl:17][c:18]1[n:19][cH:20][c:21]([C:24]([C:25]([F:26])([F:27])[F:28])([C:29]([F:30])([F:31])[F:32])[OH:33])[cH:22][n:23]1.[ClH:1].[O:43]1[CH2:44][CH2:45][O:46][CH2:47][CH2:48]1>>[CH3:2][CH:3]1[N:4]([c:18]2[n:19][cH:20][c:21]([C:24]([C:25]([F:26])([F:27])[F:28])([C:29]([F:30])([F:31])[F:32])[OH:33])[cH:22][n:23]2)[CH2:5][CH2:6][N:7]([S:9](=[O:10])(=[O:11])[c:12]2[s:13][cH:14][cH:15][cH:16]2)[CH2:8]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-047efa18804344bbaa6dfdfce612f385
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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