Potassium Cation → 4-[(6-Chloro-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]-3-fluoroaniline

HRID 299236Notes

Reaction equation

HRID 299236 reaction equation
[C:16](=[O:17])([O-:18])[O-:19].[CH3:10][C:11]([CH3:12])([O-:13])[CH3:14].[CH3:40][CH2:41][O:42][C:43](=[O:44])[CH3:45].[Cl:22][c:23]1[cH:24][c:25]([N+:32]([O-:33])=[O:34])[c:26]2[c:27]([n:28]1)[nH:29][cH:30][cH:31]2.[K+:15].[K+:20].[K+:21].[NH2:1][c:2]1[cH:3][c:4]([F:9])[c:5]([OH:8])[cH:6][cH:7]1.[O:35]=[CH:36][N:37]([CH3:38])[CH3:39]>>[NH2:1][c:2]1[cH:3][c:4]([F:9])[c:5]([O:8][c:25]2[cH:24][c:23]([Cl:22])[n:28][c:27]3[c:26]2[cH:31][cH:30][nH:29]3)[cH:6][cH:7]1

Participants

8

Reactant 7

HCID 813Potassium Cation3×HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 2735918Phenol, 4-amino-2-fluoro-HCID 45749132-Methylpropan-2-olateHCID 179793386-chloro-4-nitro-1H-pyrrolo[2,3-b]pyridine

Product 1

HCID 179792844-[(6-Chloro-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]-3-fluoroaniline

Sources & evidence

ORD record
ord-9182bb3b79854083b3b989f8f0a68acc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…