Acetic Acid → 6'-methoxy-5',7'-dimethyl-3',4'-dihydro-1'H-spiro[cyclobutane-1,2'-quinoline]
Reaction equation
[BH4-:1].[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:10][C:11](=[O:12])[OH:13].[CH3:14][O:15][c:16]1[c:17]([CH3:31])[c:18]2[c:26]([cH:27][c:28]1[CH3:29])[NH:25][C:21]1([CH2:20][CH:19]2[OH:30])[CH2:22][CH2:23][CH2:24]1.[Na+:2].[OH:3][C:4]([C:5]([F:6])([F:7])[F:8])=[O:9]>>[CH3:14][O:15][c:16]1[c:17]([CH3:31])[c:18]2[c:26]([cH:27][c:28]1[CH3:29])[NH:25][C:21]1([CH2:20][CH2:19]2)[CH2:22][CH2:23][CH2:24]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-384e2989783342e7b5233cd7b82586ae
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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