Acetate → 1-Cyclopropyl-4-(4-methoxy-benzyloxy)-1H-pyridin-2-one

HRID 299451Notes

Reaction equation

HRID 299451 reaction equation
[C:37]([O-:38])(=[O:39])[CH3:40].[C:42]([O-:43])(=[O:44])[CH3:45].[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][O:8][c:9]2[cH:10][c:11](=[O:15])[nH:12][cH:13][cH:14]2)[cH:16][cH:17]1.[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[CH3:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1.[CH:18]1([B:21]([OH:22])[OH:23])[CH2:19][CH2:20]1.[Cu+2:41].[cH:24]1[cH:25][cH:26][n:27][cH:28][cH:29]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][O:8][c:9]2[cH:10][c:11](=[O:15])[n:12]([CH:18]3[CH2:19][CH2:20]3)[cH:13][cH:14]2)[cH:16][cH:17]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 1049PyridineHCID 1140TolueneHCID 8471TriethylamineHCID 27099Cupric cationHCID 2760897Cyclopropylboronic acidHCID 66601090HCID 66601090, compound

Product 1

HCID 596358071-Cyclopropyl-4-(4-methoxy-benzyloxy)-1H-pyridin-2-one

Sources & evidence

ORD record
ord-ba0843d02f164db8bfc18ac2688637d2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…