Tetrahydrofuran → N-[2-[(5-chloro-2-pyridinyl)carbamoyl]-4-(furan-2-yl)phenyl]-1-propan-2-ylpiperidine-4-carboxamide
Reaction equation
[CH2:30]([Sn:31]([CH2:32][CH2:33][CH2:34][CH3:40])([c:35]1[o:36][cH:37][cH:38][cH:39]1)[CH2:41][CH2:42][CH2:43][CH3:44])[CH2:45][CH2:46][CH3:47].[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9]([c:10]2[c:11]([NH:17][C:18](=[O:19])[CH:20]3[CH2:21][CH2:22][N:23]([CH:26]([CH3:27])[CH3:28])[CH2:24][CH2:25]3)[cH:12][cH:13][c:14]([I:16])[cH:15]2)=[O:29])[n:6][cH:7]1.[O:48]1[CH2:49][CH2:50][CH2:51][CH2:52]1.[Pd:53]([Cl:54])[Cl:55].[c:56]1([P:57]([c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)[cH:70][cH:71][cH:72][cH:73][cH:74]1.[c:75]1([P:76]([c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)[c:83]2[cH:84][cH:85][cH:86][cH:87][cH:88]2)[cH:89][cH:90][cH:91][cH:92][cH:93]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9]([c:10]2[c:11]([NH:17][C:18](=[O:19])[CH:20]3[CH2:21][CH2:22][N:23]([CH:26]([CH3:27])[CH3:28])[CH2:24][CH2:25]3)[cH:12][cH:13][c:14](-[c:35]3[o:36][cH:37][cH:38][cH:39]3)[cH:15]2)=[O:29])[n:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-bcf4200a7e4b4ebabfe53edd079b8485
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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