4-Amino-1-(2-naphthyl)methylpiperidine → Hydrochloric Acid

HRID 29977Notes

Reaction equation

HRID 29977 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([O:12][CH3:13])[CH:10]=2)[C:5]([CH2:14][O:15][CH3:16])=[N:4][N:3]=1.[NH2:17][CH:18]1[CH2:23][CH2:22][N:21]([CH2:24][C:25]2[CH:34]=[CH:33][C:32]3[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=3)[CH:26]=2)[CH2:20][CH2:19]1>C(O)(C)C>[ClH:1].[CH3:13][O:12][C:9]1[CH:10]=[C:11]2[C:6]([C:5]([CH2:14][O:15][CH3:16])=[N:4][N:3]=[C:2]2[NH:17][CH:18]2[CH2:19][CH2:20][N:21]([CH2:24][C:25]3[CH:34]=[CH:33][C:32]4[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=4)[CH:26]=3)[CH2:22][CH2:23]2)=[CH:7][CH:8]=1.[ClH:1]

Participants

5

Reactant 2

HCID 111958234-Amino-1-(2-naphthyl)methylpiperidineHCID 576917411-Chloro-7-methoxy-4-methoxymethylphthalazine

Product 2

HCID 313Hydrochloric AcidHCID 69213386HCID 69213386, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

This compound is obtained according to the procedure described in 1.4. by reacting 1-chloro-7-methoxy-4-methoxymethylphthalazine with 4-amino-1-(naphthalen-2-ylmethyl)piperidine. The hydrochloride is obtained after treatment with a solution of hydrogen chloride in isopropanol.

Workup

  1. customThis compound is obtained

Sources & evidence

ORD record
ord-c085fe0b9ecf443f9a13075454922195
Source dataset
uspto-grants-2008_09
Patent number
US07423030B2

Reaction notes

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