Chloride → 1-Cyclopropyl-1-(4-chlorophenyl)-4-(4-fluoro-3-phenoxyphenyl)-1,3-butadiene
Reaction equation
[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH:41]1([C:44](=[CH:45][CH:46]=[O:47])[c:48]2[cH:49][cH:50][c:51]([Cl:54])[cH:52][cH:53]2)[CH2:42][CH2:43]1.[Cl-:6].[F:7][c:8]1[c:9]([O:34][c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[cH:10][c:11]([CH2:14][P+:15]([c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)([c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[cH:12][cH:13]1.[O:55]1[CH2:56][CH2:57][CH2:58][CH2:59]1>>[F:7][c:8]1[c:9]([O:34][c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[cH:10][c:11]([CH:14]=[CH:46][CH:45]=[C:44]([CH:41]2[CH2:42][CH2:43]2)[c:48]2[cH:49][cH:50][c:51]([Cl:54])[cH:52][cH:53]2)[cH:12][cH:13]1Participants
6
Sources & evidence
- ORD record
- ord-64cf78c9f276448db0188e6dad33609b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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