Benzaldehyde → 3-Bromo-5-(hydroxy(phenyl)methyl)pyridin-4-ol
Reaction equation
[Br:10][Mg:11][c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1.[Br:1][c:2]1[cH:3][n:4][cH:5][c:6]([Br:9])[c:7]1[OH:8].[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:18][CH2:19][CH2:20][CH2:21][Li:22].[CH:23](=[O:24])[c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1>>[c:2]1([CH:23]([OH:24])[c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[cH:3][n:4][cH:5][c:6]([Br:9])[c:7]1[OH:8]Participants
6
Sources & evidence
- ORD record
- ord-65b10e2f8eb7456a8430d475a722e8cd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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