Dimethylformamide → N-(3-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)phenyl)-4-(1-isopropyl-1H-pyrrolo[3,2-b]pyridin-6-yl)picolinamide

HRID 300235Notes

Reaction equation

HRID 300235 reaction equation
[CH3:70][N:71]([CH3:72])[CH:73]=[O:74].[CH:1]([CH3:2])([CH3:3])[n:4]1[cH:5][cH:6][c:7]2[n:8][cH:9][c:10](-[c:13]3[cH:14][c:15]([C:19](=[O:20])[OH:21])[n:16][cH:17][cH:18]3)[cH:11][c:12]12.[CH:22]1([n:25]2[c:26](-[c:30]3[cH:31][c:32]([NH2:33])[cH:34][cH:35][cH:36]3)[n:27][n:28][cH:29]2)[CH2:23][CH2:24]1.[CH:61]([N:62]([CH:63]([CH3:64])[CH3:65])[CH2:66][CH3:67])([CH3:68])[CH3:69].[P-:37]([F:38])([F:39])([F:40])([F:41])([F:42])[F:43].[n:44]1([O:45][C:46]([N:47]([CH3:48])[CH3:49])=[N+:50]([CH3:51])[CH3:52])[c:53]2[n:54][cH:55][cH:56][cH:57][c:58]2[n:59][n:60]1>>[CH:1]([CH3:2])([CH3:3])[n:4]1[cH:5][cH:6][c:7]2[n:8][cH:9][c:10](-[c:13]3[cH:14][c:15]([C:19](=[O:20])[NH:33][c:32]4[cH:31][c:30](-[c:26]5[n:25]([CH:22]6[CH2:23][CH2:24]6)[cH:29][n:28][n:27]5)[cH:36][cH:35][cH:34]4)[n:16][cH:17][cH:18]3)[cH:11][c:12]12

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 581029564-(1-isopropyl-1H-pyrrolo[3,2-b]pyridin-6-yl)picolinic acidHCID 581030493-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)aniline

Product 1

HCID 58102983N-(3-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)phenyl)-4-(1-isopropyl-1H-pyrrolo[3,2-b]pyridin-6-yl)picolinamide

Sources & evidence

ORD record
ord-e74c81f9c6014ac88d0fd0572c78c68b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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