Hydrochloric Acid → Dimethyl 2-(3,5-difluoro-4-(trifluoromethyl)phenyl)-piperidine-1,4-dicarboxylate
Reaction equation
[C:33]([O:34][CH3:35])(=[O:36])[Cl:37].[CH:24]([N:25]([CH2:26][CH3:27])[CH:28]([CH3:29])[CH3:30])([CH3:31])[CH3:32].[Cl:38][CH2:39][Cl:40].[ClH:1].[F:2][c:3]1[cH:4][c:5]([CH:14]2[NH:15][CH2:16][CH2:17][CH:18]([C:20](=[O:21])[O:22][CH3:23])[CH2:19]2)[cH:6][c:7]([F:13])[c:8]1[C:9]([F:10])([F:11])[F:12]>>[F:2][c:3]1[cH:4][c:5]([CH:14]2[N:15]([C:33]([O:34][CH3:35])=[O:36])[CH2:16][CH2:17][CH:18]([C:20](=[O:21])[O:22][CH3:23])[CH2:19]2)[cH:6][c:7]([F:13])[c:8]1[C:9]([F:10])([F:11])[F:12]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-a51563c1f9114f85a0e63f3bf83cd522
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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