Dimethylformamide → 4-amino-5-chloro-N-[1-(cyanomethyl)-3-methoxypiperidin-4-yl]-2-methoxybenzamide
Reaction equation
[CH3:22][N:23]([CH3:24])[CH:25]=[O:26].[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[Cl:27][CH2:28][C:29]#[N:30].[NH2:1][c:2]1[cH:3][c:4]([O:20][CH3:21])[c:5]([C:6](=[O:7])[NH:8][CH:9]2[CH:10]([O:15][CH3:16])[CH2:11][NH:12][CH2:13][CH2:14]2)[cH:17][c:18]1[Cl:19]>>[NH2:1][c:2]1[cH:3][c:4]([O:20][CH3:21])[c:5]([C:6](=[O:7])[NH:8][CH:9]2[CH:10]([O:15][CH3:16])[CH2:11][N:12]([CH2:28][C:29]#[N:30])[CH2:13][CH2:14]2)[cH:17][c:18]1[Cl:19]Participants
5
Sources & evidence
- ORD record
- ord-73505bfa3a864b25a9772187111a81cc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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